Mrs Alexandra “Alex” Quimby is the mother of Ramona and Beezus Quimby and the wife of Robert "Bob" Quimby. She is portrayed by Bridget Monayhan.

Her sister, Beatrice "Bea" Quimby, who marries her ex-boyfriend, Hobart Kemp, a few days later when Ramona runs away from the house because of her dad telling her to grow up after a water fight between the Quimby's and the Kemp's. But Hobart told Ramona that he wants to catch up with her. When Ramona tells a bad word after Bea asking her to become one of the bridesmaids, what Beezus always wanted to be, she does not accept, and walks back home after Bea broke her promise to Ramona(i.e. When Bea told Ramona that she will always have her around.)

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